Currently 1.2 million patients are receiving treatment from regenerative medicine products produced by over 150 companies with a capital value of around $4.7 billion. Most molecules, cells and tissues are collected at a given time and location for use at a later time. Therefore, our ability to stabilise biological properties (e.g. viability, biomarkers) during transportation and long-term storage is a critical technology.
"Preservation of cellular therapies" course
The University of Minnesota Biopreservation Core Resource (BioCoR) will be running another of their successful "Preservation of cellular therapies" courses on 18th-19th May 2020. The programme will cover the fundamentals of preservation, protocol development, design of a storage facility, regulatory issues associated with preservation of cell therapies, clinical issues and more. Allison Hubel, (pictured here) PhD, Professor of Mechanical Engineering and Director of the Biopreservation Core Resource (BioCoR, www.biocor.umn.edu), will be one of the programme lecturers.
Who should attend?
The course material is designed for those who have little experience with preservation, as well as those proficient in preservation who is interested in improving their practices. The preservation of cells has applications in the fields of recombinant cell biotechnology, cell banking, cell therapy, regenerative medicine and cell-based assays.
- Fundamentals of cryopreservation including mechanism of damage and strategies to prevent damaging cells during freezing, storage and warming
- Step-by-step protocol development including methods by which to construct a new preservation protocol and debugging an old protocol that is no longer working well
- Equipment, reagents and supplies used in preservation
- The challenges in implementing preservation in a clinical/GMP environment
- Fundamentals of quality control (QC) and quality assurance (QA) as well as application of the programme to preservation
- Design and operation of a storage facility for cryopreserved cells
- Regulatory issues associated with preservation of a therapeutic product
- Emerging technology and approaches for the preservation of cells